The goal of the Laboratory for Advanced Scientific Computing and Applications (LASCA) is to provide expertise and leadership in high-end scientific computing research and education at Virginia Tech. Located in the Advanced Computing and Information Technology Center (ACITC), Torgersen Hall, the laboratory is a visible and strategic center of activity in applied high-performance computing on campus. LASCA participants do basic research in high-performance parallel computation and assist scientists and engineers in applying high-end computing resources to their problems. By bringing together experts in scientific computing and its applications, LASCA helps build the kind of multidisciplinary teams needed to address today's most challenging computational science problems.